• 研究专题
  • 肿瘤
  • 自噬
  • 皮肤相关疾病
  • 化妆品体内外评价
  • 新闻中心
  • 公司要闻
  • 通知公告
  • 行业资讯
  • 联系我们
  • 当前位置: 首页  -> 产品中心 -> 雷竞技raybet官网 -> 过表达雷竞技raybet官网
    p62/SQSTM1
    时间:2019-02-15 23:01  浏览次数:802次
    Gene Name ACCN Restriction Sites TAG Selection Species Mutation/Deletion Vector Description Catalog Price
    p62/SQSTM1
    NM_001142298.1
    GFP
    None
    Human
    None
    PCMV
    2-1-009


    This gene encodes a multifunctional protein that binds ubiquitin and regulates activation of the nuclear factor kappa-B (NF-kB) signaling pathway. The protein functions as a scaffolding/adaptor protein in concert with TNF receptor-associated factor 6 to mediate activation of NF-kB in response to upstream signals. Alternatively spliced transcript variants encoding either the same or different isoforms have been identified for this gene. Mutations in this gene result in sporadic and familial Paget disease of bone.