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    IL-6
    时间:2020-01-17 20:30  浏览次数:165次
    Gene Name ACCN Restriction Sites TAG Selection Species Mutation/Deletion Vector Description Catalog Price
    IL-6
    Hygro
    Human
    PLKO.1
    3
    2-3-002-3
    This gene encodes a cytokine that functions in inflammation and the maturation of B cells. In addition, the encoded protein has been shown to be an endogenous pyrogen capable of inducing fever in people with autoimmune diseases or infections. The protein is primarily produced at sites of acute and chronic inflammation, where it is secreted into the serum and induces a transcriptional inflammatory response through interleukin 6 receptor, alpha. The functioning of this gene is implicated in a wide variety of inflammation-associated disease states, including suspectibility to diabetes mellitus and systemic juvenile rheumatoid arthritis. Alternative splicing results in multiple transcript variants.