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    PPARG
    时间:2020-01-17 20:42  浏览次数:164次
    Gene Name ACCN Restriction Sites TAG Selection Species Mutation/Deletion Vector Description Catalog Price
    PPARG
    Hygro
    Human
    PLKO.1
    3
    2-3-003-3
    This gene encodes a member of the peroxisome proliferator-activated receptor (PPAR) subfamily of nuclear receptors. PPARs form heterodimers with retinoid X receptors (RXRs) and these heterodimers regulate transcription of various genes. Three subtypes of PPARs are known: PPAR-alpha, PPAR-delta, and PPAR-gamma. The protein encoded by this gene is PPAR-gamma and is a regulator of adipocyte differentiation. Additionally, PPAR-gamma has been implicated in the pathology of numerous diseases including obesity, diabetes, atherosclerosis and cancer. Alternatively spliced transcript variants that encode different isoforms have been described.